Page Areas:



Additional Information:

Tuning membrane protein mobility by confinement into nanodomains

Hier den Alternativtext zum Bild eingeben!

[2016/11/15] In cooperation with Prof. Peter Pohl (Institute of Biophysics, JKU), lead CBL researchers DI Andreas Karner and Dr. Johannes Preiner have developed a platform to study membrane proteins. ...  more of Tuning membrane protein mobility by confinement into nanodomains (Titel)

Linz Winter Workshop 2017

Hier den Alternativtext zum Bild eingeben!

3 to 6 February 2017 ...  more of Linz Winter Workshop 2017 (Titel)

Tiemann-Boege Awarded Pilgerstorferpreis

Hier den Alternativtext zum Bild eingeben!

[2016/07/07] Assoc. Prof. Dr. Irene Tiemann-Boege was awarded the Pilgerstorferpreis from the Medical Society of Upper Austria.

Heißl awarded ÖAW Doc Scholarship

Hier den Alternativtext zum Bild eingeben!

[2016/03/04] Angelika Heißl's 3-year DOC fellowship granted by the Austrian Acadamy of Sciences (ÖAW) started on the 1 January 2016. The title is: "Meiotic recombination as a potential driver of microsatellite evolution". ...  more of Heißl awarded ÖAW Doc Scholarship (Titel)

Cholesterol in the fight against allergies

Hier den Alternativtext zum Bild eingeben!

[2016/02/15] Cholesterol in the fight against allergies ...  more of Cholesterol in the fight against allergies (Titel)

Biophysics Researchers Discover New Immune Protein Structure

Hier den Alternativtext zum Bild eingeben!

[2016/02/05] Scientists at the JKU Institute for Biophysics (a working group under a. Univ. Prof. Christoph Romanin) have deciphered a key function in the “Orai1” immune protein. ...  more of Biophysics Researchers Discover New Immune Protein Structure (Titel)

Nanopharmacological force sensing to reveal allosteric coupling in transporter binding sites

Hier den Alternativtext zum Bild eingeben!

[2016/01/26] Novel tools for direct measurement of the interaction forces between the serotonin transporter and the S- and R-enantiomers of citalopram on the single molecule level allows for the demonstration of two distinct populations of characteristic binding strengths which provide physical evidence for the existence of two binding sites that are allosterically coupled and exert reciprocal modulation. ...  more of Nanopharmacological force sensing to reveal allosteric coupling in transporter binding sites (Titel)


Position Indication:

Content

2011

Interlaboratory round robin on cantilever calibration for AFM force spectroscopy
te Riet, J., A. J. Katan, C. Rankl, S. W. Stahl, A. M. van Buul, I. Y. Phang, A. Gomez-Casado, P. Schon, J. W. Gerritsen, A. Cambi, A. E. Rowan, G. J. Vancso, P. Jonkheijm, J. Huskens, T. H. Oosterkamp, H. Gaub, P. Hinterdorfer, C. G. Figdor, and S. Speller
Ultramicroscopy, Volume 111, Issue12, pp:1659-1669. Published: December 2011.

Abstract  (Neues Fenster)

Monitoring Single Channel Water Permeability in Polarized Cells
L. Erokhova, A. Horner, P. Kügler, and P. Pohl
Journal of Biological Chemistry, Volume 286, Issue 46, pp. 39926-39932. Published: 18 November 2011.

PDF  (Neues Fenster)

A consensus segment in the M2 domain of the hP2S7 receptor shows ion channel activity in planar lipid bilayers and in biological membranes
C. Alves Magalhaes de Souza, P. Celso Nogueria Teixeira, R. X. Faria, O. Krylova, P. Pohl and L. Anastacio Alves
Biochimica et Biophysica ACTA-Biomembranes, Volume 1818, Issue 1, pp. 64-71. Published: January 2012.

Abstract  (Neues Fenster)

Molecular determinants within the N-terminus of Orai3 controlling channel activation and gating
Bergsmann J, Derler I, Muik M, Frischauf I, Fahrner M, Pollheimer PD, Gruber HJ, Groschner K, Romanin C
Journal of Biological Chemistry, Volume 286, Issue 36, pp: 31565-31575. Published: 9 September 2011.

Abstract  (Neues Fenster)

Two-dimensional kinetics of inter-connexin interactions from single-molecule force spectroscopy
Rico, F., A. Oshima, P. Hinterdorfer, Y. Fujiyoshi, and S. Scheuring
Journal of Molecular Biology, Volume 412, Issue 1, pp: 72-79. Published: 9 September 2011.

Abstract  (Neues Fenster)

Single-Molecule AFM Characterization of Individual Chemically Tagged DNA Tetrahedra
Leitner M, Mitchell N, Kastner M, Schlapak R, Gruber HJ, Hinterdorfer P, Howorka S, Ebner A
ACS Nano, Volume 5, Issue 9, pp: 7048-7054. Published: September 2011.

Abstract  (Neues Fenster)

Protons migrate along interfacial water without significant contributions from jumps between ionizable groups on the membrane surface
A. Springer, V. Hagen, D. A. Cherepanov, Y. N. Antonenko and P. Pohl
Proceedings of the National Academy of Sciences, USA, Volume 108, Issue 35, pp. 14461-14466, published 30 August 2011.
A correction was made in Volume108, Issue 44, on page 18185 on 1 November 2011.

Abstract  (Neues Fenster)

Extending optogenetics to a Ca(2+)-selective channel
Romanin, C.
Chemistry and Biology, Volume18, Issue 7, pp: 820-821. Published: 29 July 2011.

Abstract  (Neues Fenster)

PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes
Poteser, M., H. Schleifer, M. Lichtenegger, M. Schernthaner, T. Stockner, C. O. Kappe, T. N. Glasnov, C. Romanin, and K. Groschner.
Proceedings of the National Academy of Sciences USA, Volume108, Issue 26, pp: 10556-10561. Published: 28 June 2011.

Abstract  (Neues Fenster)

Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein
Riihimaki, T. A., S. Hiltunen, M. Rangl, H. R. Nordlund, J. A. Maatta, A. Ebner, P. Hinterdorfer, M. S. Kulomaa, K. Takkinen, and V. P. Hytonen
BMC Biotechnology, Volume11, Article Number: 64. Published: 9 June 2011.

Abstract  (Neues Fenster)

Sodium citrate: A universal reducing agent for reduction/decoration of graphene oxide with Au nanoparticles
Zhang Z, Chen H, Xing C, Guo M, Xu F, Wang X, Gruber HJ, Zhang B, Tang J
Nano Research, Volume 4, Issue 6, pp: 599-611. Published: June 2011.

Abstract  (Neues Fenster)

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
Muik, M., M. Fahrner, R. Schindl, P. Stathopulos, I. Frischauf, I. Derler, P. Plenk, B. Lackner, K. Groschner, M. Ikura, and C. Romanin.
EMBO Journal, Volume 30, Issue 9, pp:1678-1689. Published:4 May 2011.

Abstract  (Neues Fenster)

Linking of sensor molecules with amino groups to aminofunctionalized AFM tips
Wildling L, Unterauer B, Zhu R, Rupprecht A, Haselgrübler T, Rankl C, Ebner A, Vater D, Pollheimer P, Pohl E, Hinterdorfer P, Gruber HJ
Bioconjugate Chem. 22:1239-1248.

Abstract  (Neues Fenster)

Intrinsic CO2 Permeability of Cell Membranes and Potential Biological Relevance of CO2 Channels
W. F. Boron, V. Endeward, G. Gros, R. Musa-Aziz and P. Pohl
European Journal of Chemical Physics and Physical Chemistry, Volume 12, Issue 5, pp. 1017-1019. Published: 4 April 2011.

Abstract  (Neues Fenster)

Cooperativeness of Orai cytosolic domains tunes subtype-specific gating
Frischauf, I., R. Schindl, J. Bergsmann, I. Derler, M. Fahrner, M. Muik, R. Fritsch, B. Lackner, K. Groschner, and C. Romanin
Journal of Biological Chemistry, Volume 286, Issue10, pp:8577-8584. Published:11 March 2011.

Abstract  (Neues Fenster)

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry
Zheng, L., P. B. Stathopulos, R. Schindl, G. Y. Li, C. Romanin, and M. Ikura
Proceedings of the National Academy of Sciences, USA, Volume: 108, Issue: 4, pp: 1337-42, Published: 25 January 2011

Abstract  (Neues Fenster)

Nanoscale DNA Tetrahedra Improve Biomolecular Recognition on Patterned Surfaces
Schlapak R, Danzberger J, Armitage D, Morgan D, Pollheimer P, Gruber HJ, Schäffler F, Howorka S
Small, Volume 8, Issue 1, pp: 89-97. Published: 9 January 2012.

Abstract  (Neues Fenster)

Determination of the kinetic on- and off-rate of single virus-cell interactions.
Rankl, C., L. Wildling, I. Neundlinger, F. Kienberger, H. Gruber, D. Blaas, and P. Hinterdorfer.
Methods Mol Biol 736:197-210. Published: 2011
Abstract

Molecular recognition force spectroscopy: a new tool to tailor targeted nanoparticles.
Oliveira, H., M. Rangl, A. Ebner, B. Mayer, P. Hinterdorfer, and A. P. Pego
Small 7:1236-1241. Published: 2011
Abstract

High-frequency electromagnetic dynamics properties of THP1 cells using scanning microwave microscopy.
Oh, Y. J., H. P. Huber, M. Hochleitner, M. Duman, B. Bozna, M. Kastner, F. Kienberger, and P. Hinterdorfer
Ultramicroscopy 111:1625-1629. Published 2011.
PDF

Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1.
Krenn, B. M., Egorov, A., Romanovskaya-Romanko, E., Wolschek, M., Nakowitsch, S., Ruthsatz, T., Kiefmann, B., Morokutti, A., Humer, J., Geiler, J., Cinatl, J., Michaelis, M., Wressnigg, N., Sturlan, S., Ferko, B., Batishchev, O. V., Indenbom, A. V., Zhu, R., Kastner, M., Hinterdorfer, P., Kiselev, O., Muster, T., Romanova, J
PLoS ONE 6. Published: 2011.
Abstract

Scanning Microwave Microscopy and Scanning Capacitance Microscopy on colloidal nanocrystals.
Humer, I., Bethgea, O., Bodnarchukb, M., Kovalenkob, M., Yaremab, M., Heissb, W., Huber, H. P., Hochleitner, M., Hinterdorfer, P., Kienberger, F., Smoliner, J.
  J. Appl. Phys., 109(6):064313-064316. Published 2011.
Abstract

Characterization of enhanced monovalent and bivalent thrombin DNA aptamer binding using single molecule force spectroscopy. Neundlinger, I., A. Poturnayova, I. Karpisova, C. Rankl, P. Hinterdorfer, M. Snejdarkova, T. Hianik, and A. Ebner
Biophys J 101:1781-1787. Published: 2011.
PDF

Atomic force microscopy-based antibody recognition imaging of proteins in the pathological deposits in pseudoexfoliation syndrome.
Creasey, R., S. Sharma, C. T. Gibson, J. E. Craig, A. Ebner, T. Becker, P. Hinterdorfer, and N. H. Voelcker.
Ultramicroscopy 111:1055-1061. Published: 2011
Abstract

Binding strength and dynamics of invariant natural killer cell T cell receptor/CD1d-glycosphingolipid interaction on living cells by single molecule force spectroscopy.
Bozna, B. L., P. Polzella, C. Rankl, R. Zhu, M. Salio, D. Shepherd, M. Duman, V. Cerundolo, and P. Hinterdorfer
J Biol Chem 286:15973-15979. Published 2011.
Abstract

Nanosensing of Fcgamma receptors on macrophages.
Ahmad, S. F., L. A. Chtcheglova, B. Mayer, S. A. Kuznetsov, and P. Hinterdorfer
Anal Bioanal Chem 399:2359-2367. Published 2011
Abstract

Adjuvating the adjuvant: facilitated delivery of an immunomodulatory oligonucleotide to TLR9 by a cationic antimicrobial peptide in dendritic cells.
M. C. Aichinger, M. Ginzler, J. Weghuber, L. Zimmermann, K. Riedl, G. J. Schütz, E. Nagy, A. von Gabain, R. J. Schweyen, T. Henics.
Vaccine, Volume 29, pp. 426-436. Published 2011.
Abstract

Single molecule detection on a protein array assay platform for the exposure of a tuberculosis antigen.
R. Schmidt, J. Jacak, C. Schirwitz, V. Stadler, G. Michel, N. Marmé, G. J. Schütz, J. Hoheisel, J. P. Knemeyer.
J. Proteome Res. Volume: 10, pp.1316-1322. Published 2011.
Abstract

Spot variation fluorescence correlation spectroscopy allows for superresolution chronoscopy of confinement times in membranes.
V. Ruprecht, S. Wieser, D. Marguet, G. J. Schütz..
Biophys J. 100 (2011) 2839-2845.
Abstract

Cationic amphipatic peptides accumulate sialylated proteins and lipids in the plasma-membrane of eukaryotic host cells
Weghuber, M. C. Aichinger, M. Brameshuber, S. Wieser, V. Ruprecht, B. Plochberger, J. Madl, A. Horner, S. Reipert, K. Lohner, T. Henics, G. J. Schütz.
Biochim. Biophys. Acta 1808 (2011) 2581-2590.
Abstract

Membrane-lipid therapy in operation: The HSP co-inducer BGP-15 activates stress signal transduction pathways by remodeling plasma membrane rafts
I. Gombos, T. Crul, S. Piotto, B. Güngör, Z. Török, G. Balogh, M. Péter, J. P. Slotte, F. Campana1, A.-M. Pilbat, N. Tóth, Z. Literati-Nagy, L. Vigh Jr., A. Glatz, M. Brameshuber, G. J. Schütz, A. Hevener, M. A. Febbraio, I. Horváth, L. Vígh.
PLoS One 6 (2011) e28818.
Abstract