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Biophysics Researchers: Constant Calcium Uptake Causes Cancer in Cells

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[2017/Nov/28] Dr. Irene Frischauf and Dr. Rainer Schindl made the cover of Science Signaling with their publication: Calcium regulates many vitally important functions in the body - if the calcium balance is defective, diseases like cancer develop... ...  more of Biophysics Researchers: Constant Calcium Uptake Causes Cancer in Cells (Titel)

Noteworthy Publication in Angewandte Chemie

[2016/Nov/06] Publication in Angewandte Chemie: "Detailed Evidence for an Unparalleled Interaction Mode between Calmodulin and Orai Proteins" ...  more of Noteworthy Publication in Angewandte Chemie (Titel)

Victoria Lunz - Genuinely Passionate about Research

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[February 2017] Photo credited to OÖ Nachrichten ...  more of Victoria Lunz - Genuinely Passionate about Research (Titel)

Tuning membrane protein mobility by confinement into nanodomains

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[2016/11/16] In cooperation with Prof. Peter Pohl (Institute of Biophysics, JKU), lead CBL researchers DI Andreas Karner and Dr. Johannes Preiner have developed a platform to study membrane proteins. ...  more of Tuning membrane protein mobility by confinement into nanodomains (Titel)


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2014

Switchavidin: Reversible Biotin-Avidin-Biotin Bridges with High Affinity and Specificity
Barbara Taskinen, Dominik Zauner, Soili I. Lehtonen, Masi Koskinen, Chloe Thomson, Niklas Kahkonen, Sampo Kukkurainen, Juha A. E. Maatta, Teemu O. Ihalainen, Markku S. Kulomaa, Hermann J. Gruber, Vesa P.
Bioconjugate Chemistry, Volume: 25, Issue: 12, pp: 2233-2243, Published: December 2014.

Abstract  (Neues Fenster)

A Coiled-coil Clamp Controls Both Conformation and Clustering of Stromal Interaction Molecule 1 (STIM1) Marc Fahrner, Martina Muik, Rainer Schindl, Carmen Butorac, Peter Stathopulos, Le Zheng, Isaac Jardin, Mitsuhiko Ikura, Christoph Romanin.
Journal of Biological Chemistry, Volume: 289, Issue: 48, Pages: 33231-33244 Published: 28 Nov 2014

Abstract  (Neues Fenster)

TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival
Maylis Raphael, V'yacheslav Lehen'kyi, Matthieu Vandenberghe, Benjamin Beck, Sergiy Khalimonchyk, Abeele, Fabien Vanden, Leonardo Farsetti, Emmanuelle Germain, Alexandre Bokhobza, Adriana Mihalache, Pierre Gosset, Christoph Romanin, Philippe Clezardin, Roman Skryma, Natalia Prevarskaya.
PNAS, Volume: 111, Issue: 37, pp: E3870-E3879, Published: 16 September 2014

Abstract  (Neues Fenster)

Ion Conductivity of the Bacterial Translocation Channel SecYEG Engaged in Translocation
Denis G. Knyazev, Lukas Winter, Benedikt W. Bauer, Christine Siligan, and Peter Pohl
J. Biol. Chem., 29 August 2014, 289, pp. 24611-24616

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Forces and Dynamics of Glucose and Inhibitor Binding to Sodium Glucose Co-transporter SGLT1 Studied by Single Molecule Force Spectroscopy
Isabel Neundlinger, Theeraporn Puntheeranurak, Linda Wildling, Christian Rankl, Lai-Xi Wang, Hermann J. Gruber, Rolf K.H. Kinne, Peter Hinterdorfer.
Journal of Biological Chemistry, Volume: 289, Issue: 31, pp: 21673-21683, Published: 1 August 2014.

Abstract  (Neues Fenster)

IgGs are made for walking on bacterial and viral surfaces
Johannes Preiner, Noriyuki, Jilin L. Tang, Andreas Ebner, Mario Brameshuber, Dieter Blaas, Nicola Gelbmann, Hermann J. Gruber, Toshio Ando, Peter Hinterdorfer.
Nature Communications, Volume: 5, Article No.: 4394, Published: July 2014.

Abstract  (Neues Fenster)

Complex role of STIM1 in the activation of store-independent Orai1/3 channels
Xuexin Zhang, Wie Zhang,Jose C.Gonzalez-Cobos, Isaac Jardin, Christoph Romanin, Khalid Matrougui, Mohamed Trebak.
Journal of General Physiology, Volume: 143, Issue: 3, pp: 345-359, Published: March 2014

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Investigating the binding behaviour of two avidin-based testosterone binders using molecular recognition force spectroscopy
Martina Rangl, Michael Leitner, Tiina Riihimaki, Soili Lehtonen, Vesa P. Hytonen, Hermann J Gruber, Markku Kulomaa, Peter Hinterdorfer, Andreas Ebner.
Journal of Molecular Recognition, Volume: 27, Issue: 2 pp: 92-97, Published: February 2014

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Kinetics of bioconjugate nanoparticle label binding in a sandwich-type immunoassay
Tuomas Nareoja, Andreas Ebner, Hermann J. Gruber, Barbara Taskinen, Ferry Kienberger, Pekka E. Hanninen, Vesa P.Hytonen, Peter Hinterdorfer, Harri Harma.
Analytical and Bioanalytical Chemistry, Volume: 406, Issue: 2 pp: 493-503, Published: January 2014

Abstract  (Neues Fenster)

Real-Time Monitoring of Membrane-Protein Reconstitution by Isothermal Titration Calorimetry
Nadin Jahnke, Oxana O. Krylova, Torben Hoomann, Carolyn Vargas, Sebastian Fiedler, Peter Pohl, and Sandro Keller
Anal. Chem., 2014, 86 (1), pp 920–927. 7 January 2014.

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