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Inaugural Biochemistry Symposium

Puzzles of (Bio)molecular Structure and Dynamics: NMR spectroscopy and complementary approaches 

 

At the 23rd and 24th of May 2023 a symposium is held on the occasion of the opening the new Institute of Biochemistry at JKU with its head Prof. Frans A.A. Mulder.
The symposium focusses at molecular structure, dynamics and function.

Fifteen renowned international scientists will present the application of structural and biophysical methods to biochemistry at the molecular level, encompassing NMR spectroscopy, X-ray crystallography, cryo-EM, molecular simulations, and complementary methods.

Central to the symposium is the quest for a quantitative description of biological phenomena at the molecular level.

Program

Location: Uni-Center Loft at  Johannes Kepler University campus.

Date: 23 - 24 May 20023

Book of Abstracts: (Download, opens a file)

Tuesday, 23 May 2023

   
10:00  registration opens + coffee
10:25          opening
session 1: NMR, metabolites & cells (chair: Adriana Rathner)
10:30 Marco Tessari, Radboud Universiteit, Nijmegen (NL)
NMR Discrimination of enantiomers at sub-micromolar concentration via parahydrogen-Induced hyperpolarization
11:10 Simone Fjordside, Aarhus University/Novo Nordisk A/S (DK)
Metabolic Profiling of a Hepatic ER Stress Model
11:30 Claudio Luchinat, CERM/CIRMMP, Università di Firenze (IT)
Metabolomics by NMR: achievements and perspectives
12:10 lunch & poster session
session 2: protein structure & dynamics with NMR (chair: Mario Schubert)
13:30 Claire Raingeval, Aarhus University (DK)
Accurate extraction of site‑specific methyl deuterium quadrupolar patterns: from simulation to experiment
13:50 Paul Schanda, Institute of Science and Technology, Klosterneuburg (AT)
NMR in solution and solids: playing with spins and isotopes to resolve biological mechanisms
14:30 Klaartje Houben, DSM Science & Innovation, Delft (NL)
Characterization of food proteins and enzymes
15:10 tea break - group photo
session 3: protein structure & dynamics with X-rays (chair: Robert Konrat)
15:40 Martin Weik, IBS, Grenoble (FR) 
Making molecular movies of proteins at work using bright X-ray sources
16:20 Jean van den Elsen, University of Bath (UK)
Compounds from the cowshed: designing novel complement inhibitors
17:00 free time / check-in at hotel
18:45 Pöstlingbergbahn Special service from Hauptplatz, opens an external URL in a new window to Pöstlingberg
19:00 dinner at Pöstlingberg Schlössl, opens an external URL in a new window
22:45 Pöstlingbergbahn Special service from Pöstlingberg , opens an external URL in a new windowto Hauptplatz
 (earlier service at own cost or walking , opens an external URL in a new windowdown anytime possible)

 

Wednesday, 24 May 2023

   
session 4: dynamics & recognition (chair: Remco Sprangers)
09:00          Mikael Akke, Lund Universitet (SE)
Protein–ligand binding studied by NMR
09:40 Lars Schäfer, Ruhr University, Bochum (DE)
NMR experiments and MD simulations: A Love Relation?
10:20 coffee break
session 5: structure & design (chair: Rob Kaptein)
10:50 Ingemar André, Lund Universitet (SE)
Design and prediction of the structure of protein containers
11:30 Marco Sette, Università di Roma "Tor Vergata", Rome (IT)
NMR for therapeutical peptides
12:10 lunch & poster session
session 6: proteins, RNA, and electrostatics (chair: Norbert Müller)
13:10 Rolf Boelens, Universiteit Utrecht (NL)
Structure and dynamics in gene regulation
13:50 Anthony Mittermaier, McGill University (CA)
Dynamics of Guanine Quadruplexes
14:30 Lewis E. Kay, University of Toronto (CA)
Using magnetic fields to probe electric fields of biomolecules
15:10 closing remarks
15:20 symposium ends + short tours at the Institute of Biochemistry
TNF tower, 5th floor    (refreshments & snacks provided)

 

Important Dates

   
Registration Opening: 05.04.2023
Registration Deadline: 01.05.2023

 

Registration

Regular 150 EUR
Regular (with GÖCH membership) 130 EUR
Student 75 EUR
Student (with GÖCH membership) 60 EUR
Invited speaker 0 EUR
Selected presentation only 0 EUR

 

For registration to the Inaugural Biochemistry Symposium the following steps are necessary:

  1. Create a new user account via https://conferences.jku.at/bionmr/user/register, opens an external URL in a new window. Here you receive an email with a link that leads you to a page where you can set a password. Another option is to login with Shibboleth (JKU employees only)
  2. Login with you username and password via https://conferences.jku.at/bionmr/user/login, opens an external URL in a new window
  3. Register to the conference via "My registration" -> "Event registration"

Participents will get an automated confirmation email of the registration. If this does not happen, please send an email to bionmr(at)jku.at to make sure the orgaiser has received your registration. Your registration will only be complete once the full payment has been made. Please indicate any corrections to you registration to bionmr(at)jku.at.

  • EPS
  • PayPal
  • Credit Card

Cancellation must be submitted in writing to bionmr(at)jku.at no later than 08.05.2023. No refunds will be processed after this date. All refunds will be managed after the conference.

If you cannot attend, your registration is transferable to some other person whom you must indicate to us in your cancellation request (name, affiliation, address, email).

The organizer reserves the right to modify the content of the program, the speakers and the times of presentations. In the case of a cancellation by the organizer, participants will be reimbursed the registration fee actually paid.

Poster Session

  1. Abi Saad, Marie Jose: Unlocking the Potential of Allosteric Inhibitors for Future Pandemics: Targeting the Main protease of SARS-CoV-2
  2. Baumgartner, Manuel: INVESTIGATING THE ACTIVATION OF A CALCIUM SENSOR PROTEIN DIMER CONNECTED AT THE N-TERM
  3. Buhl, Julie: The power of co-solute PRE in NMR
  4. Cabrera, Andrea: Intermolecular dynamics and allostery of human BRD4-BD1 and -BD2
  5. Fjordside, Simone: A Real-Time Approach to Study Cellular Metabolism in Liver Cells
  6. Gemmecker, Gerd: Investigating ligand‐induced conformational changes in the tRNA‐guanine transglycosylase dimer by 19F NMR
  7. Giri, Malyasree: Probing electrostatics from salt-dependent hydrogen exchange rates in the unfolded protein state
  8. Gubensäk, Nina: Vibrio cholerae's ToxRS Bile Sensing System
  9. Hejduk, Libor: Do structural differences of Decorin binding proteins from European Borrelia genospecies influence glycosaminoglycanes binding?
  10. Holzinger, Julian: RDCs and the Order of the PROTAC
  11. Kadeřávek, Pavel: Domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis beyond its major state conformation
  12. Krempl, Christina    Combining NMR and smFRET experiments to study the conformations of the Dcp1:Dcp2 mRNA decapping complex
  13. Napoli, Federico     Long-range coupling in a dodecameric enzyme complex unraveled by solid-state NMR
  14. Pantoja, Christian Felipe    NMR spectroscopy to study the thermodynamics of liquid-liquid phase separation of human Tau protein
  15. Raingeval, Claire    Accurate extraction of site‑specific methyl deuterium quadrupolar patterns: from simulation to experimentation
  16. Rathner, Adriana    EXPLORING INTERACTIONS OF ADHESINS FROM PATHOGENIC BORRELIA
  17. Rohden, Darja    Synthesis and Incorporation of Arginine with Specific Isotope Patterns to Study Protein Dynamics by NMR
  18. Schmalix, Alexander    Regulation of Nedd4 family E3 ubiquitin ligases through auto-inhibition
  19. Schneider, Jakob    Substrate binding of the 65 kDa cytosolic domain of Tom70 studied by NMR spectroscopy
  20. Tužinčin, D.    Domain 1.1 of σ A factor of RNA polymerase from Bacillus subtilis beyond its major state conformation
  21. Wilson, Russell J.    2D Mechanoresponsive Surfaces for Measuring Cellular Traction Forces

Travelling

Linz is reachable by plane or train.


By plane


Linz-Hörsching airport , opens an external URL in a new windowis connected by bus 601, opens an external URL in a new window (hourly) to the city center (main station) and has connections from Frankfurt. Vienna airport has a direct train connection to Linz Hbf (main station) and is well connected. Salzburg airport is connected through bus and train to Linz and has connections to the rest of Europe.

By train

Austria has two main trainlines (ÖBB, opens an external URL in a new window and Westbahn, opens an external URL in a new window) and is therefore well-connected throughout Austria and to surrounding countries.

Getting to JKU

The app ÖBB Scotty, opens an external URL in a new window can be used for public transportation. Tramline 1 and 2 go to JKU Linz as well as bus 315. Tickets can be bought at tramline stops, Hauptbahnhof (main station) or using the app LinzMobil. Citybikes are available and can be rented through the app nextbike by TIER.

If you would like to pre-order a taxi at Linz airport, then you can call taxi Haas tel: +43 7229 69296

Accomodation

Special booking arrangements have been made with the following Hotels:

Hotel Sommerhaus, opens an external URL in a new window
Single room: € 62,00/night incl. breakfast
Double rooms: € 94,00/night incl. breakfast
Discount code valid until: 21. April 2023
Use the code bionmr2023 for booking via hotel(at)studentenwerk.at

Harrys Home, opens an external URL in a new window
Single rooms: 114,00/night incl. breakfast (excl. city tax of € 2,20 per night/person
Discount code valid until: 02. Mai 2023
Use the code bionmr2023 for booking via reservierung(at)harrys-home.com
 
Goldener Adler, opens an external URL in a new window
Single room: € 85,00/night incl. breakfast 
Discount code valid until: 20. April 2023
Use the code bionmr2023 for booking via office(at)goldeneradler.at

Earlier arrival and departure are possible upon request.

Contact Information

Evelyn Pirklbauer

Institute of Biochemistry
University of Linz
Altenberger Str. 69
A-4040 Linz, Austria

Tel.: +43 (0)732 2468 9301
Email: bionmr(at)jku.at

 

Sponsors:

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