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Institute of Pharmacology
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  1. B. Hoeger, S. Zierler (2022) Engulf and digest – TRPM7 as key regulator of macrophage phagosome maturation. Science Direct, 2022102636

  2. Spix B., Butz E.S., Chen C.C., Plesch E., Wartenberg P., Scotto Rosato A., Arlt E., Briukhovetska D., Jeridi A., Wyatt A., Kissing S., Teupser D., Holdt L.M., Boehm U., García-Añoveros J., Saftig P., Schiller H.B., Kobold S., Boekhoff I., Zierler S., Wahl-Schott C., Gudermann G., Bracher F., Yildirim A.Ö., Biel M., Grimm C. Impaired MMP-12 clearance and emphysema-like phenotype in mucolipin 3 deficient mice. Nature Communications 2022, 13(1):318. doi: 10.1038/s41467-021-27860-x

  3. Steiner, P., E., Arlt, I., Boekhoff, T., Gudermann and S., Zierler. 2022. Two-pore channels regulate inter-organellar Ca2+ homeostasis in immune cells. Cells (Review, in preparation)

  4. T. Shahin, D. Mayr, M.R. Shoeb, H.S. Kuehn, B. Hoeger, …, S.D. Rosenzweig, K. Boztug (2021) Identification of Germline Monoallelic Mutations in IKZF2 in Patients with Immune Dysregulation. Blood Advances, 2021006367.

  5. T. Shahin, H.S. Kuehn, M.R. Shoeb, Gawriyski L., Giuliani S., Repiscak P, B. Hoeger, Ö.Y. Petronczki, S. Köstel Bal, S. Zoghi, J. Dmytrus, D. Seruggia, I. Castanon, N. Rezaei, M. Varjosalo, F. Halbritter, S.D. Rosenzweig, K. Boztug (2021) Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity. Science Immunology 6, 65.

  6. Steiner, P.+, O., Buchner+, A., Andosch, A., Holzinger, U., Lütz-Meindl and G., Neuner. 2021. Winter survival of the unicellular green alga Micrasterias denticulata: insights from field monitoring and simulation experiments. Protoplasma. 259:1335. (+ Joint first authors)

  7. Michelini, S., F. Barbero, A. Prinelli, P. Steiner, R. Weiss, T. Verwanger, A. Andosch, U. Lütz-Meindl, V. F. Puntes, D. Drobne, A. Duschl, J. Horejs-Hoeck. 2021. Gold nanoparticles (AuNPs) impair LPS-driven immune responses by promoting a tolerogenic-like dendritic cell phenotype with altered endosomal structure. Nanoscale. 13:7648.

  8. Nadolni W., Immler R., Hoelting K., Fraticelli M., Ripphahn M., Rothmiller S., Matsushita M., Boekhoff I., Gudermann T., Sperandio M., Zierler S. TRPM7 Kinase is essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling. Frontiers in Immunology  2021 doi: 10.3389/fimmu.2020.606893

  9. E. Salzer, S. Zoghi, M.G. Kiss, F. Kage, C. Rashkova, S. Stahnke, M. Haimel, R. Platzer, M. Caldera, R.C. Ardy, B. Hoeger, J. Block, D. Medgyesi, C. Sin, S. Shahkarami, R. Kain, V. Ziaee, P. Hammerl, C. Bock, J. Menche, L. Dupre, J.B. Huppa, M. Sixt, A. Lomakin, K. Rottner, C.J. Binder, T.B. Stradal, N. Rezaei, K. Boztug (2020) The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology 5, eabc3979.

  10. M. Thian, B. Hoeger, A. Kamnev, F. Poyer, S. Köstel Bal, M. Caldera, R. Jimenez Heredia, J. Huemer, W.F. Pickl, M. Groß, S. Ehl, C.L. Lucas, J. Menche, C. Hutter, A. Attarbashi, L. Dupre, K. Boztug (2020) Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation. Haematologica 105, e488.

  11. Arlt E., Fraticelli M., Tsvilovskyy V., O’Neill T.J., Wennemuth G., Breit A., Wahl-Schott C., Biel M., Freichel M., Grimm C., Gudermann T., Klugbauer N., Boekhoff I, Zierler S. Targeting the two-pore channel TPC1 augments systemic anaphylaxis and mast cell activity. Proceedings of the National Academy of Sciences of the United States of America 2020 117:18068-18078. doi: 10.1073/pnas.1920122117

  12. Gerndt S., Chen C., Chao Y., Yuan Y., Burgstaller S., Scotto Rosato A., Krogsaeter E., Urban N., Jacob K., Nguyen O.N.P., Miller M.T., Keller M., Vollmar A.M., Gudermann T., Zierler S., Schredelseker J., Schaefer M., Biel M., Malli R., Wahl-Schott C., Bracher F., Patel S., Grimm C. Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function. eLife, 2020 doi: 10.7554/eLife.54712

  13. Steiner, P., O., Buchner, A., Andosch, G., Wanner, G., Neuner and U., Lütz-Meindl. 2020. Fusion of mitochondria to 3-D networks, autophagy and increased organelle contacts are important subcellular hallmarks during cold stress in plants. International Journal of Molecular Science. 21:8753.

  14. Steiner, P., S. Obwegeser, G. Wanner, O. Buchner, U. Lütz-Meindl and A. Holzinger. 2020. Cell wall reinforcements accompany chilling and freezing stress in the streptophyte green alga Klebsormidium crenulatum. Frontiers of Plant Science. 11:873.

  15. Buchner+, O. & P. Steiner+, A. Andosch, A. Holzinger, M. Stegner, G. Neuner and U. Lütz-Meindl. 2020. A new technical approach for preparing frozen biological samples for electron microscopy. Plant Methods. 48:16. (+ Joint first authors)