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Forschungsprojekte

Permeation durch den bakteriellen Harnstofftransporter UreI FWFP31074

Protonengradienten in bakterieller Proteintranslokation FWFP29841

Publikationen zu FWFP29841

DK NanoCell

Laterale Protonenmigration entlang von Membranen FWFP25981

Publikationen zu FWFP25981

Zhang C., Nguyen T., Weichselbaum E., Knyazev D., Pohl P., Carloni P.:
Interfacial water molecules at biological membranes: Structural features and role for lateralproton diffusionCa, in Plos one, 2018

Pashkovskaya A., Vazdar M., Zimmermann L., Jovanovic O., Pohl P., Pohl E.:
Mechanism of Long-Chain Free Fatty Acid Protonation at the Membrane-Water Interface, in Biophysical Journal, 2018

Österbauer M., Weichselbaum E., Pohl P., Knör G.:
Caged Protons as Tools for Studying Transport of Protons along Lipid Bilayers, in Biophys. J., Vol. 112, Seite(n) 277a, 2017

Weichselbaum E., Österbauer M., Knyazev D., Batishchev O., Akimov A., Nguyen T., Zhang C., Knör G., Agmon N., Carloni P., Pohl P.:
Origin of proton affinity to membrane/water interfaces, in Scientific Reports - Nature, Vol. 7, Seite(n) 4553, 2017

Weichselbaum E., Österbauer M., Knör G., Pohl P.:
Regulation of Proton Migration along the Membrane Surface, in Biophys. J., Vol. 112, Seite(n) 277a, 2017

Agmon N., Bakker H., Campen R., Henchman R., Pohl P., Roke S., Thämer M., Hassanali A.:
Protons and Hydroxide Ions in Aqueous Systems, in Chem. Rev., Vol. 116, Nr. 13, Seite(n) 7642–7672, 2016

Spannungsabhängig-keit des Proteintransloka-tionskanals (SecY) FWFP28213

Publikationen zu FWFP28213

Kopplungsmechanismen zwischen Membranmonoschichten FWFI2267

Publikationen zu FWFI2267

Pohl P., Horner A.:
Unitary Water Channel Permeability and Arrhenius Activation Energy are Intricately Linked, in Biophysical Journal, 2018

Galimzyanov T., Kuzmin P., Pohl P., Akimov A.:
Undulations Drive Domain Registration from the Two Membrane Leaflets, in Biophysical Journal, Nr. 112, Seite(n) 339-345, 2017

Galimzyanov T., Kuzmin P., Pohl P., Akimov A.:
Elastic deformations of bolalipid membranes, in Soft Matter, Vol. 12, Seite(n) 2357-2364, 2016

Akimov A., Pohl P., Galimzyanov T., Molotkovsky R., Bozdaganyan M., Cohen F.:
Elastic Membrane Deformations Govern Interleaflet Coupling of Lipid-Ordered Domains, in Physical Review Letters (PRL), Seite(n) 088101-1-5, 2015

Wassertransport durch den Natrium-Glukose-Cotransporter FWFP23574

Publikationen zu FWFP23574

Wasser- und Gastransport durch Aquaporine FWFP23466

Publikationen zu FWFP23466

Horner A., Siligan C., Pohl P., Cornean V.:
Positively charged residues at the channel mouth boost single-file water flow, in Faraday Discussions, 2018

Horner A., Pohl P.:
Single-file transport of water through membrane channels, in Faraday Discussions, 2018

Horner A., Zocher F., Preiner J., Ollinger N., Siligan C., Akimov A., Pohl P.:
The mobility of single-file water molecules is governed by the number of H-bonds they may form with channel-lining residues, in Sci. Adv., Serie e1400083, Vol. 1, Seite(n) 1-5, 2015

Preiner J., Horner A., Karner A., Ollinger N., Siligan C., Pohl P., Hinterdorfer P.:
High-speed AFM images of thermal motion provide stiffness map of interfacial membrane protein moieties, in Nano Letters, Vol. doi: 10.1021/nl504478f, American Chemical Society, 2014

Zocher F., van der Spoel D., Pohl P., Hub J.:
Local Partition Coefficients Govern Solute Permeability of Cholesterol-Containing Membranes, in Biophysical Journal, Vol. 105, Nr. 12, Seite(n) 2760-70, 2013

Zocher F., Zeidel M., Missner A., Tung-Tien S., Ge Z., Yi L., von Bodungen M., Hill W., Meyers S., Pohl P., Mathai J.:
Uroplakins do not restrict CO2 transport through the urothelium, in The Journal of biological chemistry, 2012

Erokhova L., Horner A., Kugler P., Pohl P.:
Monitoring single-channel water permeability in polarized cells, in Chem.J. Biol. Chem., 2011
 

Leitfähigkeit des SecY Proteintranslokationskanals FWFP20872

Publikationen zu FWFP20872

Winter L., Knyazev D., Vogt A., Kuttner R., Ollinger N., Siligan C., Pohl P., Koch H., Sachelaru I.:
YidC and SecYEG form a heterotetrameric protein translocation channel, in Nature Scientific Reports, 2017

Knyazev D., Winter L., Bauer B., Siligan C., Pohl P.:
Ion Conductivity of the Bacterial Translocation Channel SecYEG Engaged in Translocation, in Journal of Biological Chemistry, Serie 289, Vol. 38, Seite(n) 24611-24616, 2014

Knyazev D., Lents A., Krause E., Ollinger N., Siligan C., Papinski D., Winter L., Horner A., Pohl P.:
The bacterial translocon SecYEG opens upon ribosome binding, in The Journal of Biological Chemistry, Vol. 288, Nr. 25, Seite(n) 17941-6, 2013

 

Single-File Wassertransport durch Nanoporen FWFP23679

Publikationen zu FWFP23679

Horner A., Pohl P.:
Comment on "Enhanced water permeability and tunable ion slectivity in subnanometer carbon nanotube porins, in Science, 2018

Tarun O., Hannesschläger C., Pohl P., Roke S.:
Label-free and charge-sensitive dynamic imaging of lipid membrane hydration on millisecond time scales, in PNAS, 2018

Bellissent-Funel M., Hassanali A., Havenith M., Henchman R., Pohl P., Sterpone F., van der Spoel D., Xu Y., Garcia A.:
Water Determines the Structure and Dynamics of Proteins, in Chem. Rev., Seite(n) 7673–7697, 2016

Horner A., Zocher F., Preiner J., Ollinger N., Siligan C., Akimov A., Pohl P.:
The mobility of single-file water molecules is governed by the number of H-bonds they may form with channel-lining residues, in Sci. Adv., Serie e1400083, Vol. 1, Seite(n) 1-5, 2015

Portella G., Polupanow T., Zocher F., Boytsov D., Pohl P., Diederichsen U., de Groot B.:
Design of Peptide-Membrane Interactions to Modulate Single-File Water Transport through Modified Gramicidin Channels, in Biophysical Journal, Serie 103, Vol. 8, Seite(n) 1698-705, 2012

 

Wassertransport durch Kaliumkanäle FWFP19716 

Publikationen zu FWFP19716

Molecular Bioanalytics FWFW1201

Publikationen zu FWFW1201

Antonenko Y., Horner A., Pohl P.:
Electrostatically Induced Recruitment of Membrane Peptides into Clusters Requires Ligand Binding at Both Interfaces, in PLOS One, Serie 7, Vol. 12, 2012

Erokhova L., Horner A., Kugler P., Pohl P.:
Monitoring single-channel water permeability in polarized cells, in Chem.J. Biol. Chem., 2011

Missner A., Pohl P.:
110 Years of the Meyer-Overton Rule: Predicting membrane permeability of gases and other small compounds, in Journal of Chemical Physics and Physical Chemistry (ChemPhysChem), 2009

Horner A., Antenenko Y., Pohl P.:
Coupled diffusion of peripherally bound peptides along the outer and inner membrane leaflets, in Biophysical Journal, 2009

Mathai J., Missner A., Kügler P., Saparov S., Zeidel M., Lee J., Pohl P.:
No facilitator required for membrane transport of hydrogen sulfide, in Proceedings of the National Academy of Sciences (PNAS), 2009

Missner A., Kügler P., Saparov S., Sommer K., Mathai J., Zeidel M., Pohl P.:
Carbon dioxide transport through mebranes, in Journal of Biological Chemistry, 2008

Agre P., Liu K., Pohl P., Saparov S.:
Fast and selective ammonia transport by aquaporin-8, in J.Biol.Chem., Vol. 282, Seite(n) 5296-5301, 2007

 

Nanobatterieplattform

Assoz. Univ. Prof. Dr. Andreas Ebner

PROTON - Proton transport and proton-coupled transport