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Publikationen.

Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells.

  • Henze LA, Luong TTD, Boehme B, Masyout J, Schneider MP, Brachs S, Lang F, Pieske B, Pasch A, Eckardt KU, Voelkl J, Alesutan I.
  • Aging (Albany NY). 2019 Aug 3;11(15):5445-5462. doi: 10.18632/aging.102130.

 

Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment

  • Schanstra JP, Luong TT, Makridakis M, Van Linthout S, Lygirou V, Latosinska A, Alesutan I, Boehme B, Schelski N, Von Lewinski D, Mullen W, Nicklin S, Delles C,  Feuillet G, Denis C, Lang F, Pieske B, Bascands JL, Mischak H, Saulnier-Blache JS, Voelkl J, Vlahou A, Klein J.
  • JCI Insight. 2019 May 16;4(10). pii:  125638. doi: 10.1172/jci.insight.125638. eCollection 2019 May 16. PubMed PMID: 31092728; PubMed Central PMCID: PMC6542631.

 

SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.

  • Voelkl J, Luong TT, Tuffaha R, Musculus K, Auer T, Lian X, Daniel C, Zickler D, Boehme B, Sacherer M, Metzler B, Kuhl D, Gollasch M, Amann K, Müller DN, Pieske B, Lang F, Alesutan I.
  • J Clin Invest. 2018 Jul 2;128(7):3024-3040. doi: 10.1172/JCI96477. Epub 2018 Jun 11. PubMed PMID: 29889103; PubMed Central PMCID: PMC6025998.

 

Fibulin-3 Attenuates Phosphate-Induced Vascular Smooth Muscle Cell Calcification by Inhibition of Oxidative Stress.

  • Luong TTD, Schelski N, Boehme B, Makridakis M, Vlahou A, Lang F, Pieske B, Alesutan I, Voelkl J.
  • Cell Physiol Biochem. 2018;46(4):1305-1316. doi: 10.1159/000489144. Epub 2018 Apr 18. PubMed PMID: 29689558.

 

Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB.

  • Voelkl J, Tuffaha R, Luong TTD, Zickler D, Masyout J, Feger M, Verheyen N, Blaschke F, Kuro-O M, Tomaschitz A, Pilz S, Pasch A, Eckardt KU, Scherberich JE,  Lang F, Pieske B, Alesutan I.
  • J Am Soc Nephrol. 2018 Jun;29(6):1636-1648. doi: 10.1681/ASN.2017050492. Epub 2018 Apr 13. PubMed PMID: 29654213; PubMed Central PMCID: PMC6054342.

 

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells.

  • Alesutan I, Voelkl J, Feger M, Kratschmar DV, Castor T, Mia S, Sacherer M, Viereck R, Borst O, Leibrock C, Gawaz M, Kuro-O M, Pilz S, Tomaschitz A, Odermatt A, Pieske B, Wagner CA, Lang F.
  • Sci Rep. 2017 May 17;7(1):2059. doi: 10.1038/s41598-017-01882-2. PubMed PMID: 28515448; PubMed Central PMCID: PMC5435689.

 

Inhibition of osteo/chondrogenic transformation of vascular smooth muscle cells by MgCl2 via calcium-sensing receptor.

  • Alesutan I, Tuffaha R, Auer T, Feger M, Pieske B, Lang F, Voelkl J.
  • J Hypertens. 2017 Mar;35(3):523-532. doi: 10.1097/HJH.0000000000001202. PubMed PMID: 27984337.

 

Augmentation of phosphate-induced osteo-/chondrogenic transformation of vascular smooth muscle cells by homoarginine.

  • Alesutan I, Feger M, Tuffaha R, Castor T, Musculus K, Buehling SS, Heine CL, Kuro-O M, Pieske B, Schmidt K, Tomaschitz A, Maerz W, Pilz S, Meinitzer A, Voelkl J, Lang F.
  • Cardiovasc Res. 2016 Jun 1;110(3):408-18. doi: 10.1093/cvr/cvw062. Epub 2016 Mar 21. PubMed PMID: 27001421.

 

NH4Cl Treatment Prevents Tissue Calcification in Klotho Deficiency.

  • Leibrock CB, Alesutan I, Voelkl J, Pakladok T, Michael D, Schleicher E, Kamyabi-Moghaddam Z, Quintanilla-Martinez L, Kuro-o M, Lang F.
  • J Am Soc Nephrol. 2015 Oct;26(10):2423-33. doi: 10.1681/ASN.2014030230. Epub 2015 Feb 2. PubMed PMID: 25644113; PubMed Central PMCID: PMC4587682.

 

Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice.

  • Voelkl J, Alesutan I, Leibrock CB, Quintanilla-Martinez L, Kuhn V, Feger M, Mia S, Ahmed MS, Rosenblatt KP, Kuro-O M, Lang F.
  • J Clin Invest. 2013 Feb;123(2):812-22. doi: 10.1172/JCI64093. Epub 2013 Jan 9. PubMed PMID: 23298834; PubMed Central PMCID: PMC3561808.