schliessen

Prof. Dr. Peter Pohl

Leitung

Curriculum Vitae

Head of the Institute of Biophysics, Johannes Kepler University (JKU) Linz, Austria; Head of the Division of Molecular Biophysics and Membrane Biophysics; Institut of Biophysics, JKU Linz; Full Professor of Biophysics, Department of Physics, JKU, Austria

Group Leader, Leibnitz Institute for Melicular Pharmacology

Interims Chair for Experimental Biophysics at the Humboldt University Berlin

Assistant Professor, Institute of Medical Physics and Biophysics, Martin-Luther University, Halle, Germany

Research Scientist, Institute of Applied Biophysics, Martin-Luther-University, Hallo, Germany

Alles zeigen

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Publikationen

Horner A., Pohl P., (2018) Single-file transport of water through membrane channels.Faraday Discussions, 10.1039/C8FD00122G

Horner A., Siligan,C., Cornean A., Pohl P. (2018) Positively charged residues at the channel mouth boost single-file water flow, Faraday Discuss,10.1039/C8FD00050F 

Knyazev D., Kuttner R.,  Zimmermann M., Sobakinskaya E., Pohl P., (2018) Driving Forces of Translocation Through Bacterial Translocon SecYEG. The Journal of membran biology, 251(3):329-343. doi: 10.1007/s00232-017-0012-9

Tarun O.B., Hannesschlaeger C., Pohl P., Roke S., (2018) Label-free and charge-sensitive dynamic imaging of lipid membrane hydration on millisecond time scales. PNAS,  201719347

Pashkovskaya A., Vazdar M., Zimmermann L., Jovanovic O., Pohl P., Pohl E., (2018) Mechanism of Long-Chain Free Fatty Acid Protonation at the Membrane-Water Interface. Biophysics Journal ,114(9):2142-2151. doi: 10.1016/j.bpj.2018.04.011

Nguyen T., Zhang C., Weichselbaum E., Knyazev D., Pohl P., Carloni P., (2018) Interfacial water molecules at biological membranes: Structural features and role for lateral proton diffusion. PLOS ONE,13 (2), e0193454

Horner A.,  Pohl P., (2018)  Comment on “Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins”. Science, Vol. 359, Issue 6383, eaap9173 DOI: 10.1126/science.aap9173

Horner A., Pohl P., (2018) Unitary Water Channel Permeability and Arrhenius Activation Energy are Intricately Linked. Biophys. J., 114:493A-494A

Timur R., Peter I., Pohl P., Sergey A., (2018) Undulations Drive Domain Registration from the Two Membrane Leaflets.  Biophysical Journal,Volume 112, pp. 339-345

Karner A., Nimmervoll B., Plochberger E., Klotzsch A., Horner A., Knyazev D., Kuttner R., Winkler K.,  Winter L., Siligan C., Ollinger N., Pohl P., Preiner J.;  (2017) Tuning membrane protein mobility by confinement into nanodomains.Nat. Nanotech, 12:260-266.

Sachelaru I., Winter L., Knyazev D., Vogt A., Kuttner R., Ollinger N., Siligan C., Pohl P., Koch H., (2017) YidC and SecYEG form a heterotetrameric protein translocation channel. Sci. Reports. 7:101

Weichselbaum E., Österbauer M., Knyazev D., Batishchev O.,  Akimov S., Nguyen T., Zhang C., Knör, G., Agmon N., Carloni P., and Pohl P., (2017)  Origin of proton affinity to membrane/water interfaces. Sci. Reports. In press, DOI:10.1038/s41598-017-04675-9.

Knyazev D., Kuttner R., Zimmermann M., Sobakinskaya E., Pohl P., (2017)  Driving Forces of Translocation Through Bacterial Translocon SecYEG.

Karner A., Nimmervoll B., Plochberger B., Klotzsch E., Horner A., Knyazev D., Kuttner R., Winkler K., Winter L., Siligan C., Ollinger N., Pohl P., Preiner J., (2016)  Tuning membrane protein mobility by confinement into nanodomain. Nature Nanotechnology. 2016 Nov 14. doi: 10.1038/nnano.2016.236

Agmon N., Huib J. Bakker, R., Campen K., Henchman R., Pohl P., Roke S., Thämer M., Hassanali A.,(2016)  Protons and Hydroxide Ions in Aqueous Systems. Chem. Rev. DOI: 10.1021/acs.chemrev.5b00736

Sokolov V., Gavrilchik A., Kulagina A., Meshkova I.,  Pohl P., Gorbunova Y., (2016)  Voltage-sensitive styryl dyes as singlet oxygen targets on the surface of bilayer lipid membrane. Journal of Photochemistry and Photobiology, Volume 161, pp. 162-169

Bellissent-Funel M., Hassanali A., Havenith M., Henchman R., Pohl P., Sterpone F., David van der Spoel, Yao Xu, and Angel E Garcia (2016) Water Determines the Structure and Dynamics of Proteins. Chem. Rev.

Erokhova L., Horner A., Ollinger N., Siligan C., Pohl P., (2016)  The Sodium Glucose Cotransporter SGLT1 is an Extremely Efficient Facilitator of Passive Water Transport. J Biol Chem., 291 (18), pp. 9712-20

Galimzyanov T., Molotkovsky R., Cohen F., Pohl P., Akimov S., (2016) Comment on "Elastic Membrane Deformations Govern Interleaflet Coupling of Lipid-Ordered Domains" Reply. Phys.Rev. 

Galimzyanov T.,  Kuzmin P., Pohl P., Akimov S., (2016) Elastic deformations of bolalipid membranes.  Soft Matter, 12, 2357-2364

Galimzyanov T., Molotkovsky R., Bozdaganyan M., Cohen F., Pohl P., Akimov S., (2015) Elastic Membrane Deformations Govern Interleaflet Coupling of Lipid-Ordered. Physical Review Letters 115, 088101

Horner A., Zocher F., Preiner J., Ollinger N., Siligan C., Akimov S., Pohl P.,(2015) The mobility of single-file water molecules is governed by the number of H-bonds they may form with channel-lining residues. Sci. Adv. Vol. 1, no. 2

Preiner J., Horner A., Karner A., Ollinger N., Siligan C., Pohl P., Hinterdorfer P.,(2015)  High-Speed AFM Images of Thermal Motion Provide Stiffness Map of Interfacial Membrane Protein Moieties.   Nano Letters, Volume: 15, Issue: 1, pp: 759-763

Knyazev D., Winter L., Bauer B., Siligan C., Pohl P., (2014)  Ion Conductivity of the Bacterial Translocation Channel SecYEG Engaged in Translocation. J. Biol. Chem., 289, pp. 24611-24616

Jahnke N., Krylova O., Hoomann T., Vargas C., Fiedler S., Pohl P., Keller S., (2014) Real-Time Monitoring of Membrane-Protein Reconstitution by Isothermal Titration Calorimetry Anal. Chem., 86 (1), pp 920–927.

Preiner J., Horner A., Karner A., Öllinger N,. Siligan C., Pohl P., Hinterdorfer P., (2014) High-speed AFM images of thermal motion provide stiffness map of interfacial membrane protein moieties. Nano Letters , 2015, 15 (1), pp 759–763

Hoomann T., Jahnke N., Horner A., Keller S., Pohl P.,(2013)  Filtergate closure inhibits ion but not water transport through potassium channels. Proc. Natl. Acad.Sci.U.S.A. 10 (26): 10842-10847, Published online 2013 Jun 10. doi:  10.1073/pnas.1304714110

Knyazev D., Lents A., Krause E., Ollinger N., Siligan C., Papinski D., Winter L., Horner A., Pohl P., (2013) The Bacterial Translocon SecYEG Opens upon Ribsome Binding. J.Biol.Chem. 288(25):17941-17946

Zocher F., Spoel D., Pohl P., Hub J., 82013) Local Partition Coefficients Govern Solute Permeability of Cholesterol-Containing Membranes. Biophys J. 105:2760-2770

Horner A., AkimovS., Pohl P., (2013) Long and short lipid molecules experience the same interleaflet drag in lipid bilayers. Phys.Rev.Lett. 110(26):26810, Published online 2013 Jun 24. 

Zhang C., Knyazev D., Vereshaga Y., Ippoliti E., Nguyen T., Carloni P., Pohl P., (2012) Water at hydrophobic interfaces delays proton surface-to-bulk transfer and provides a pathway for lateral proton diffusion. Proc Natl Acad Sci U S A, PNAS June 19, 2012. 109 (25) 9744-9749

Zhang C., Knyazev D., Vereshaga Y., Ippoliti E., Nguyen T., Carloni P., Pohl P., (2012) Water at hydrophobic interfaces delays proton surface-to-bulk transfer and provides a pathway for lateral proton diffusion. Proc Natl Acad Sci U S A, PNAS June 19, 2012. 109 (25) 9744-9749

Horner A., Goetz F., Tampe R., Klussmann E., Pohl P., (2012) Mechanism for targeting the A-kinase anchoring protein AKAP18 δ to the membrane. JBiol Chem 287:42495-42501

Portella G., Polupanow T., ZocherF., Boytsow D., Pohl P., Diederichsen U., Groot B., (2012) Design of Peptide-Membrane Interactions to Modulate Single-File Water Transport through Modified Gramicidin Channels. Biophys J. 103:1698-1705

Springer A., Hagner V., Cherepanov D., Antonenko Y., Pohl P., (2011) Protons migrate along interfacial water without significant contributions from jumps between ionizable groups on the membrane surface. PNAS August 30, 2011. 108 (35) 14461-14466

Springer A.,Hagen V., Cherepanov D., Antonenko Y., Pohl P., (2011) Protons migrate along interfacial water without significant contributions from jumps between ionizable groups on the membrane surface. Proc Natl Acad Sci U S A 108:14461-14466

Boron W., Endeward V., Gros G., Musa-Aziz R., Pohl P., (2011) Intrinsic CO2 Permeability of Cell Membranes and Potential Biological Relevance of CO2 Channel. ChemPhysChem 12:1017-1019.

Erokhova L., Horner A., Kugler P., Pohl P., (2011) Monitoring single-channel water permeability in polarized cells. J Biol Chem 286:39926-39932

Mathai J., Missner A., Kügler P., Saparov S., Zeidel M., Lee J., Pohl P., (2009) No facilitator required for membrane transport of hydrogen sulfide. Proc. Natl. Acad. Sci. U.S.S.

Saparov S., Erlandson K., Canon K., Schaletzky J., Schulman S., Raport T., Pohl P., (2007) Determining the Conductance of the SecY Protein Translocation Channel for Small Molecule. Mol.Cell 26:501-509

Saparov S. Pfeifer J., Al-Momani L., Portella G., Groot B., Koert U., Pohl P., (2006) Mobilityofa one-dimensional confined file of water molecules as a function of file length. Phys.Rev.Lett. 96(14):148101

Saparov S., Pohl P., (2004) Beyond the diffusion limit: Water flow through the empty bacterial potassium channel. Proc. Natl. Sci. USA 101:4805-4809

Sekretariat, Laborantinnen und Techniker

  Name Funktion Raum Durchwahl E-Mail
  Marijana Saric Sekretariat 018 7561 marijana.saric@jku.at
  Ing. Christine Furherr Sekretariat, Labor 018 7560 christine.furherr@jku.at
  Bettina Kenda-Nistelberger Labor 010 7576 bettina.kenda-nistelberger@jku.at
  Siegfried Minich Techniker 218 7625 siegfried.minich@jku.at

Wissenschaftliche MitarbeiterInnen

Name

Funktion

Raum

Durchwahl

E-Mail

Assist. Prof. Dr. Andreas Horner

Assistenz Professor

312

7575

andreas.horner@jku.at

Dr.in Christine Siligan

Senior lecturer

016

7578

christine.siligan@jku.at

Dipl. Ing. Dr. Christof Hannesschläger

Universitätsassistent

007

7571

Christof.Hannesschlaeger@jku.at

Dr. Denis Knyazev

Post Doc

015

7573

denis.knyazev@jku.at

Dipl. Phys. Danila Boytsov             

Doktorand

008

7574

danila.boytsov@jku.at

Mag. Roland Kuttner

Doktorand

 

7640

roland.kuttner@jku.at

Ali Saitov MSc            

Doktorand

007

7572

ali.saitov@jku.at

Dipl. Ing. Ewald Weichselbaum

Doktorand

008

7550

ewald.weichselbaum@jku.at

Mirjam Zimmermann MSc

Doktorand

433

 

7642

 

mirjam.zimmermann@jku.at

Thomas Barta BSc

Masterstudent

008

  thomas.barta@jku.at

Lawrence "Rudy" Cadena BSc

Masterstudent

008