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PUBLICATION LIST

Books

  • Tiemann-Boege Irene, Betancourt Andrea (Eds.) (2017) Haplotyping - Methods and Protocols. Methods in Molecular Biology, vol. 1551, DOI 10.1007/978-1 -4939-6750-6_1 ®Springer Science+Business Media LLC 2017

Peered reviewed journals

  • Tiemann-Boege I, Schwarz T, Striedner Y, Heissl A. (2017) The consequences of sequence erosion in the evolution of recombination hotspots. Philos Trans R Soc Lond B Biol Sci. 19;372(1736). pii: 20160462. doi: 10.1098/rstb.2016.0462. Review
     
  • Weth A., Dippl C., Striedner Y., Tiemann-Boege I., Vereshchaga J., Golenhofen N., Bartelt-Kirbach B., and Baumgartner W. Water transport through the intestinal epithelial barrier under different osmotic conditions is dependent on LI-cadherin trans-interaction. Tissue Barriers, 2017
     
  • Striedner Y., Schwarz T., Welte T., Futschik A., Rant U, and Tiemann-Boege I. (2017) The long zinc finger domain of PRDM9 forms a highly stable and long-lived complex with its DNA recognition sequence. Chromosome Research. 2017 Feb 2. doi: 10.1007/s10577-017-9552-1. PMID: 28155083
     
  • Palzenberger E., Reinhardt R., Muresan L., Palaoro B., and Tiemann-Boege I. (2017) Discovery of rare haplotypes by typing millions of single-molecules with bead emulsion haplotyping (BEH). Methods in Molecular Biology, 1551:273-305
     
  • Arbeithuber B, Heissl A., Tiemann-Boege I. (2017) Haplotyping of heterozygous SNPs in genomic DNA using long range PCR. Methods in Molecular Biology, 1551: 3-22
     
  • Heissl A., Arbeithuber B, Tiemann-Boege I. (2017) High-Throughput Genotyping with TaqMan Allelic Discrimination and Allele-Specific Genotyping Assays. Methods Mol Biol;1492:29-57.
     
  • Arbeithuber B, Makova KD, Tiemann-Boege I. (2016) Artifactual mutations resulting from DNA lesions limit detection levels in ultrasensitive sequencing applications. DNA Res. 2016 Dec;23(6):547- 559
     
  • Arbeithuber B, Betancourt AJ, Ebner T, Tiemann-Boege I. (2015) Crossovers are associated with mutation and biased gene conversion at recombination hotspots. Proc Natl Acad Sci U S A. 112(7):2109-14
     
  • Arbeithuber B, Thuenauer R, Gravogl Y, Balogi Z, Sonnleitner A, Tiemann-Boege I. (2015) Aquaporin 5 Expression in Mouse Mammary Gland Cells Is Not Driven by Promoter Methylation. BioMed Research International, Volume 2015, Article ID 460598
     
  • Shinde DN*, Elmer DP*, Calabrese P, Boulanger J, Arnheim N, Tiemann-Boege I. (2013) New evidence for positive selection helps explain the paternal age effect observed in achondroplasia. Hum Mol Genet 22: 4117-4126
    *Joint first authorship.
     
  • Meyer WK, Arbeithuber B, Ober C, Ebner T, Tiemann-Boege I, Hudson RR, Przeworski M (2012) Evaluating the evidence for transmission distortion in human pedigrees. Genetics 191: 215-232
     
  • Boulanger J, Muresan L, Tiemann-Boege I. (2012) Massively parallel haplotyping on microscopic beads for the high-throughput phase analysis of single molecules. PLoS One 7: e36064
     
  • Tiemann-Boege I., Curtis C, Shinde DN, Goodman DB, Tavare S, Arnheim N (2009) Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel. Anal Chem 81: 5770-5776
     
  • Qin J, Calabrese P, Tiemann-Boege I., Shinde DN, Yoon SR, Gelfand D, Bauer K, Arnheim N (2007) The molecular anatomy of spontaneous germline mutations in human testes. PLoS Biol 5: e224
     
  • Clark VJ, Ptak SE, Tiemann I., Qian Y, Coop G, Stone AC, Przeworski M, Arnheim N, Di Rienzo A (2007) Combining sperm typing and linkage disequilibrium analyses reveals differences in selective pressures or recombination rates across human populations. Genetics 175: 795-804
     
  • Tiemann-Boege I., Calabrese P, Cochran DM, Sokol R, Arnheim N (2006) High-resolution recombination patterns in a region of human chromosome 21 measured by sperm typing. PLoS Genet 2: e70
     
  • Wyrobek AJ, Eskenazi B, Young S, Arnheim N, Tiemann-Boege I., Jabs EW, Glaser RL, Pearson FS, Evenson D (2006) Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm. Proc Natl Acad Sci U S A 103: 9601-9606
     
  • Arnheim N, Calabrese P, Tiemann-Boege I. (2007) Mammalian meiotic recombination hot spots. Annu Rev Genet 41: 369-399
     
  • Tiemann-Boege I., Navidi W, Grewal R, Cohn D, Eskenazi B, Wyrobek AJ, Arnheim N (2002) The observed human sperm mutation frequency cannot explain the achondroplasia paternal age effect. Proc Natl Acad Sci U S A 99: 14952-14957
     
  • Tiemann-Boege I., Kilpatrick CW, Schmidly DJ, Bradley RD (2000) Molecular phylogenetics of the Peromyscus boylii species group (Rodentia: muridae) based on mitochondrial cytochrome b sequences. Mol Phylogenet Evol 16: 366-378
     
  • Bradley RD, Tiemann-Boege I., Kilpatrick C, Schmidly D (2000) Taxonomic status of Peromyscus boylii sacarensis: inferences from DNA sequences of the mitochondrial cytochrome b gene. Journal of Mammalogy 81: 875-884
     
  • Bradley RD, Carroll DS, Clary ML, Edwards CW, Tiemann-Boege I., Hamilton MJ, Van Den Busche RA, Jones C (1999) Comments on some small mammals from the Big Bend and Trans-Pecos regions of Texas. Occasional Papers of the Museum of Texas Tech University 193
     
  • Bradley RD, Martinez R, Maltbie M, Tiemann-Boege I., Wichman HA, Baker RJ (2003) Rapidly evolving repetitive DNA in a karyotypically megaevolved genome: factors that affect chromosomal evolution. Occasional Papers of the Museum of Texas Tech University 223
     
  • Clary ML, Bell DM, Edwards CW, Jolley TW, Knyazhnitskiy O, Lewis-Oritt N, Mantooth SJ, Peppers LL, Tiemann-Boege I., Yancey I, Frank D., Howell DJ, Locke BA, Baker RJ, Bradley RD (1999) Checklist of mammals from twelve habitat types at Fort Bliss Military Base. Occasional Papers of the Museum of Texas Tech University 192
     
  • Hilber W., Tiemann-Boege I., Diskus C., Lederer T., Jakoby B.: Parallel DNA Amplification Using Localized Microwave Heating in Standard Microtubes: Proc. of the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS) , Page(s) 88-90
     
  • Tiemann-Boege I., Curtis C, Shibata D, Tavare S (2008) High-throughput analysis of methylation patterns to track cell divisions. Cellular Oncology 30: 229

 

Thesis

  • Tiemann-Boege, I. Quantification of Mutations Causing Achondroplasia: a Study of the Paternal Age Effect. 2003. University of Southern California, Los Angeles, USA. Advisor: Norman Arnheim
     
  • Tiemann-Boege, I. Molecular systematics of the Peromyscus boylii species group. 1999. Texas Tech University, Lubbock, USA. Advisor: Robert D. Bradley
     
  • Tiemann-Boege, I. DNA sequence recognition by monoclonal anti-dsDNA antibodies. 1997. Universidad de las Américas, Puebla, Mexico. Advisor: Javier Garcés-Eisele

 

Abstracts in Scientific Meetings/Workshops

  • Selected Talk
    Changes in the FGFR3 signaling cause muations to expand with age in the male germline
    Irene Tiemann-Boege, Renato Salazar, barbara Arbeithuber, Angelika Heissl and Theresa Schwarz
    Austrian Association of Molecular Life Sciences and Biothechnology 2017. Innsbruck, Austria
    2017, Aug 27-31
     
  • Short tandem repeats and their manifold influence on human meiotic recombination, (Poster)
    Angelika Heissl, Andrea Betancourt, and Irene Tiemann-Boege
    EMBO Meiosis 2017, Hvar, Croatia
    2017, Aug 27-31
     
  • Characterization of the PRDM9 zinc-finger array binding and multimer formation, (Poster)
    Theresa Schwarz, Yasmin Striedner, Karin Dungl, and Irene Tiemann-Boege
    EMBO Meiosis 2017, Hvar, Croatia
    2017, Aug 27-31
     
  • Invited Talk
    Evolutionary causes and consequences of variation in recombination rateIrene
    Tiemann-Boege
    ESEB, Groningen, The Netherlands
    2017, Aug 20-25
     
  • Discovery of selfish mutations with ultra sensitive sequencing, (Poster)
    Renato Salazar, Barbara Arbeithuber, and Irene Tiemann-Boege
    German Society of Human Genetics, Bochum, Germany
    2017, Mar 29-31
     
  • Characterization of the PRDM9 zinc-finger array binding and multimer formation, (Talk)
    Theresa Schwarz and Irene Tiemann-Boege
    Central European Genome Stability and Dynamics Meeting, Zagreb, Craotia
    2016, Oct 15-16
     
  • Meiotic recombination is an important driver of sequence evolution at hotspots (Poster)
    Barbara Arbeithuber, Angelika Heissl, and Irene Tiemann-Boege
    American Association of Human Genetics, Vancouver, Canada
    2016, October 18-22
     
  • Invited TalkSequence evolution at recombination hotspots
    Irene Tiemann-Boege
    The 7thEMBO Meeting, Mannheim, Germany
    2016, September 10-13
     
  • Meiotic recombination as a potential driver of short tandem repeat evolution (Poster)
    Angelika Heissl, Barbara Arbeithuber, and Irene Tiemann-Boege
    Abcam-Mechanisms of Recombination, Alicante, Spain
    2016, May 16-19
     
  • Biochemical characterization of the PRDM9 Zinc-Finger array binding (Poster)
    Theresa Schwarz, Yasmin Striedner, Hermann Gruber, Irene Tiemann-Boege
    EMBO Meiosis Conference 2015, Oxford, UK
    2015, Aug 30 - Sept 4
     
  • Exploring the DNA-binding specificities and kinetics of the Zinc Finger protein PRDM9 (Poster)
    Yasmin Striedner, Theresa Schwarz, Thomas Welte, Ulrich Rant, Irene Tiemann-Boege
    EMBO Meiosis Conference 2015, Oxford, UK
    2015, Aug 30 - Sept 4
     
  • Selected talk
    The evolution of short indels at meiotic recombination hotspots
    Angelika Heissl, Barbara Arbeithuber, Irene Tiemann-Boege.
    Society of Molecular Biology and Evolution (SMBE) Meeting, Vienna, Austria.
    2015, July 12-16
     
  • Characterizing the Zinc Finger Binding Interactions of PRDM9 with DNA (Talk)
    Yasmin Gravogl, Theresa Schwarz, Irene Tiemann-Boege
    5th Central European Genome Stability and Dynamics Meeting, Brno, Check Republic
    2014, Oct 9-10
     
  • Crossovers are associated with mutation and biased gene conversion at recombination hotspots (Talk)
    Barbara Arbeithuber, Andrea Betancourt, Irene Tiemann-Boege
    5th Central European Genome Stability and Dynamics Meeting, Brno, Check Republic
    2014, Oct 9-10
     
  • Characterizing the Zinc Finger Binding Interactions of PRDM9 with DNA (Talk)
    Yasmin Gravogl, Theresa Schwarz, Irene Tiemann-Boege
    5th Central European Genome Stability and Dynamics Meeting, Brno, Check Republic
    2014, Oct 9-10
     
  • Crossovers are associated with mutation and biased gene conversion at recombination hotspots (Talk)
    Barbara Arbeithuber, Andrea Betancourt, Irene Tiemann-Boege
    5th Central European Genome Stability and Dynamics Meeting, Brno, Check Republic
    2014, Oct 9-10
     
  • Selected talk Assessment of PRDM9 Zinc Finger binding with DNA of Recombination Hotspots
    Theresa Schwarz, Yasmin Gravogl, Irene Tiemann-Boege.
    6th OEGMBT annual meeting Life Sciences Meet Entrepreneurship", Vienna, Austria
    2014, Sept 15 - 18
  • Characterizing the Zinc Finger Binding Interactions of PRDM9 with the DNA of Recombination Hotspots.
    Yasmin Gravogl, Theresa Schwarz, Irene Tiemann-Boege
    FEBS–EMBO 2014 Conference, Paris, France
    2014, Aug 30 - Sept 4
     
  • What factors drive the evolution of human meiotic recombination hotspots?
    Barbara Arbeithuber, Andrea J. Betancourt, Thomas Ebner, Irene Tiemann-Boege.

    Mechanisms of Recombination: 50th Anniversary Meeting of the Holliday Model, Alicante, Spain. 2014, Mai 19-24 (Poster)

    DK SAB meeting 2014, Vetmeduni Vienna, Vienna, Austria. 2014, May 14-16 (Talk)
     
  • Mutations and Biased Gene Conversion drive the evolution of human meiotic recombination hotspots
    Barbara Arbeithuber, Andrea J Betancourt, Thomas Ebner, Irene Tiemann-Boege.
    Cold Spring Harbor Laboratory-CSHL The Biology of Genomes, Cold Spring Harbor, USA
    2014, May 6-10
     
  • Establishing a system to characterize the Zinc Finger Binding Interactions of PRDM9 with the DNA of Recombination Hotspots.
    Yasmin Gravogl, Theresa Schwarz, Hermann Gruber, Irene Tiemann-Boege.
    XVI. Annual Linz Winter Workshop, Linz, Austria
    2014, Jan 31 - Feb 3
     
  • How recombination reshapes our genome
    Barbara Arbeithuber, Thomas Ebner, Irene Tiemann-Boege
    Central European DNA repair Meeting, Vienna, Austria.
    2013, Nov 08
     
  • Analysis of de novo mutations in meiotic crossover products
    Barbara Arbeithuber, Thomas Ebner, and Irene Tiemann-Boege.

    European Molecular Biology Organization EMBO-Meiosis, Dresden, Germany 2013, Sept 14-19

    Society of Molecular Biology and Evolution (SMBE) Meeting, Chicago, USA. 2013, July 07-11
     
  • Quantification and characterization of de novo mutations in human meiotic recombination.
    Barbara Arbeithuber, Thomas Ebner, Irene Tiemann-Boege.
    Next Generation Sequencing Workshop, Hinxton, UK.
    2013, Mar 25-27
     
  • Down-regulation of AQP5 is not correlated with significant changes in promoter methylation“.
    Barbara Arbeithuber, Roland Thuenauer, Zsolt Balogi, Alois Sonnleitner, Irene Tiemann-Boege.

    FEBS International Workshop on "New Developments in RNA Biology", Algarve, Portugal 2012,Sept 1-4

    The EMBO Meeting 2012, Nice, France. 2012, Sept 22-25
     
  • Selfish mutations in the human germline.
    Deepali N. Shinde, Peter Calabrese, Dominik Elmer, Norman Arnheim, Irene Tiemann-Boege.
    Gordon Research Conferences- Mutagenesis, Newport, USA
    2012, Aug 19-24
     
  • Characterizing the Zinc Finger Binding Interactions of PRDM9 with the DNA of Recombination Hotspots.
    Yasmin Gravogl, Petko Petkov, Irene Tiemann-Boege.
    EMBO PEPC8 (Protein Expression, Purification and Characterization), Hamburg, Germany
    2012, Sept 3-11
  • Is transmission distortion in humans driven by meiosis?
    Barbara Arbeithuber, Wynn K. Meyer, Molly Przeworski, and Irene Tiemann-Boege.
    European Molecular Biology Organization EMBO Meiosis, Capaccio/Paestum, Italy
    2011, Sept 17-21
     
  • Selected talk
    Screening meiotic recombination on microscopic beads 2010
    Irene Tiemann-Boege
    Austrian Association of Molecular Life Sciences and Biotechnology, Vienna, Austria
    2010, Sept  
     
  • Parallel DNA amplification using localized microwave heating in standard microtubes.
    Hilber W, Tiemann-Boege I., Diskus C, Lederer T, Jakoby B.
    14th Int. Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), Groningen, Neatherlands
    2010, Oct 3-7
     
  • A new sperm typing technology based on micro PCR reactors to analyze recombination hotspots.
    Tiemann-Boege I., Jérôme Boulanger, and Leila Muresan. 
    Gordon Research Conference-GRC Meiosis, New London, USA
    2010, June 13-18
     
  • High throughput digital readout of methylation patterns using bead emulsion amplification.
    Tiemann-Boege I, Curtis C, Tavare S.
    Gordon Research Conference in Human Genetics and Genomics, Biddeford, USA
    2009, June 19-24
     
  • Selected talk
    High throughput analysis of methylation patterns to track stem cell divisions.
    Tiemann-Boege I, Curtis C, Darryl Shibata, Tavare S.Marie Curie--
    Genome architecture in relation to disease, Madrid, Spain.
    2008, May 4-7
     
  • Analysis of fine scale recombination in a region of chromosome 21.
    Tiemann-Boege I, Calabrese P, Cochran DM, Sokol R, and Arnheim N.
    HapMap Meeting, Cambridge, MA, USA
    2006, May 8-10
     
  • Selected talk Analysis of fine structure recombination patterns in a human chromosomal region not previously known to harbor a recombination hot spot.
    Tiemann-Boege I, Calabrese P, Cochran DM, Sokol R, and Arnheim N.
    55th Meeting of the American Society of Human Genetics. Platform Session, Salt lake City, USA
    2005, Oct 25-29
     
  • Mutation frequency cannot explain the achondroplasia age effect.
    Tiemann-Boege I, Navidi W, and Arnheim N.
    43rd Annual Course in Mammalian Genetics, Jackson Laboratories, Bar Harbor, ME, USA
    2002, July 16-24
     
  • Selected talk (Best presentation award)
    Molecular phylogenetics of the Peromyscus boylii species group.
    Tiemann-Boege I, Kilpatrick CW, Schmidly DJ, Bradley DJ.
    American Society of Mammalogists, Seattle, WA, USA
    1999, July 12-16
     
  • Phylogenetics of the Peromyscus boylii species group using cytochrome b sequences.
    Tiemann-Boege I, Schmidly DJ, Bradley RD.
    Texas Society of Mammalogists, Junction, Texas, USA.
    1999, February 14-16
     
  • Estado taxonómico y distribución del grupo Peromyscus boylii de México.
    Tiemann-Boege I, Kilpatrick CW, Schmidly DJ, Bradley RD.
    Third National Conference of mammology, Asociación Mexicana de Zoología, Xalapa, Mexico.
    1998, Nov 23-27
     
  • Sequence specificity of a monoclonal anti-dsDNA antibody.
    Tiemann-Boege I, Alarcón-Segovia D, Ruiz-Argüelles A, Garcés-Eisele J.
    Fifth International Conference on Systemic Lupus Erythematosus, Cancun, Mexico.
    1998, April 20-25